Effectiveness of Varicella Vaccine

The varicella vaccine has been used in the United States because 1995 for stopping chickenpox, also recognized as varicella. Like other vaccines, the varicella vaccine provokes an immune reaction that prospects to the manufacturing of protecting antibodies. If you are uncovered to varicella after being vaccinated, these antibodies will understand the virus and ruin it before it can make you ill. Since its introduction, varicella vaccine has sharply decreased the incidence of chickenpox in the United States.

Vaccine Advantages

Chickenpox is caused by the varicella-zoster virus. Preliminary infection leads to headache, fever, physique aches and a attribute rash that lasts two to three months. Varicella is rarely severe in healthy children, but complications such as pneumonia, anxious system damage or even death sometimes occur. Adults, newborns and kids with weak immune systems are especially susceptible to varicella problems. In accordance to an August 2011 review in "Pediatrics," use of the varicella vaccine has led to a almost ninety percent reduction in varicella-related fatalities in all age teams.

Learning Curve

During its initial decade of use in the United States, varicella vaccine was administered as a one-time injection. This plan reduced the death price from varicella by approximately 66 %. Nevertheless, research showed that 15 to 20 percent of children who received 1 dose of vaccine still contracted chickenpox simply because they did not develop a protective immune response after a single injection. Present varicella vaccination protocols suggest two independent injections, which improves the immune response and could conceivably eliminate fatalities and serious problems because of to varicella.

Questions Remain

Twenty years does not provide enough time to totally assess the dangers and benefits of a vaccination program. A study published in March 2007 in "The New England Journal of Medicine" shown that immunity to varicella waned a number of years following a solitary vaccination, leaving many immunized people susceptible to infection. This is an problem that prompted the recommendation for a booster vaccination for all previously immunized kids and adults. It is still too early to know whether or not a booster will confer lengthy-term immunity for vaccinated individuals.


The Facilities for Disease Manage and Avoidance suggests healthy kids who have not had chickenpox obtain their initial varicella vaccine in between the ages of 12 and 15 months. A second dose should be administered between the ages of four and six years. Capture-up vaccinations are available for kids, adolescents and grownups who had been not immunized according to these recommendations. Expecting ladies and people with impaired immunity ought to not receive varicella vaccine.
If you or your child has not obtained the varicella vaccine, speak with your doctor about the potential dangers and advantages.